Autor(es): Duarte,Tiago ; Caeiro,Fernando ; Góis,Mário ; Matos,António ; Viana,Helena ; Vieira,César ; Paulos,Jorge ; Paixão,Paulo ; Matos,Bruno ; Germano,Nuno ; Nolasco,Fernando
Data: 2021
Origem: SciELO Portugal
Assunto(s): acute kidney injury; COVID-19; kidney biopsy
ABSTRACT SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.
