Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection

• Autor(es): Dias Da Costa, Mariana ; Leal Rato, Miguel ; Cruz, Diana ; Valadas, Anabela ; Antunes, Ana Patrícia ; Albuquerque, Luísa
• Data: 2021
• Identificador Persistente: http://hdl.handle.net/10451/50690
• Origem: Repositório da Universidade de Lisboa
• Assunto(s): COVID-19; MOG-IgG; Myelitis; Post-infectious myelitis; SARS-CoV-2
• Tipo de Documento: Artigo científico
• Idioma: Inglês
• Contribuidor(es): Repositório Científico de Acesso Aberto da ULisboa

Descrição

We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid therapy in this setting. Further prospective studies are needed to establish the risk of recurrence in this subset of patients.