Author(s): Souza, Geane Felix de ; Barbosa, Maritza Cavalcante ; Santos, Talyta Ellen de Jesus ; Carvalho, Teresa Maria de Jesus Ponte ; Freitas, Rivelilson Mendes de ; Martins, Manoel Ricardo Alves ; Gonçalves, Romélia Pinheiro ; Pinheiro, Ronald Feitosa ; Magalhães, Silvia Maria Meira
Date: 2014
Origin: Oasisbr
Subject(s): Estresse Oxidativo; Ferro
Myelodysplastic syndromes (MDS) are group of stem cell disorders characterised by peripheral cytopaenias and a variable risk of progression to acute myeloid leukaemia. Most patients have anaemia and many develop transfusion dependence and iron overload (IOL), considered to be a negative independent prognostic factor associated with a higher risk of leukemic transformation and shorter survival.
