Autor(es): Vieira, Raquel ; Souto, Selma B. ; Sánchez-López, Elena ; Machado, Ana López ; Severino, Patrícia ; Jose, Sajan ; Santini, Antonello ; Fortuna, A. ; García, Maria Luisa ; Silva, Amelia M. ; Souto, Eliana B.
Data: 2019
Identificador Persistente: https://hdl.handle.net/10316/107210
Origem: Estudo Geral - Universidade de Coimbra
Assunto(s): diabetes mellitus; metabolic syndrome; glucose-lowering agents; sugar-lowering oils; phytotherapy
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia together with disturbances in the metabolism of carbohydrates, proteins and fat, which in general results from an insulin availability and need imbalance. In a great number of patients, marketed anti-glycemic agents have shown poor effectiveness in maintaining a long-term glycemic control, thus being associated with severe adverse effects and leading to an emerging interest in natural compounds (e.g., essential oils and other secondary plant metabolites, namely, flavonoid-rich compounds) as a novel approach for prevention, management and/or treatment of either non-insulin-dependent diabetes mellitus (T2DM, type 2 DM) and/or Metabolic Syndrome (MS). In this review, some of these promising glucose-lowering agents will be comprehensively discussed.
Project M-ERA-NET/0004/2015-PAIRED and UID/AGR/04033/2019 (CITAB), and Institute of Nanoscience and Nanotechnology under the project ART(2018).
