Author(s):
Valdiglesias, Vanessa ; Fernández-Bertólez, Natália ; Touzani, A. ; Mendéz, J. ; Martinez, L. ; Pásaro, E. ; Reis, A.T. ; Fraga, S. ; Teixeira, J.P. ; Costa, C. ; Laffon, B.
Date: 2023
Persistent ID: http://hdl.handle.net/10400.18/9056
Origin: Repositório Científico do Instituto Nacional de Saúde
Subject(s): Metal-based Nanoparticles; Comet Assay; DNA Primary Damage; DNA Oxidative Damage; Metal Nanoparticles; Salivary Leucocytes; Genotoxicidade Ambiental; Biomonitoring; Human Exposure
Description
Metal-based nanoparticles (NP) are being increasingly used in a wide variety of applications in consumer products and biomedical practices. As a result, human exposure to these nanomaterials is frequent, becoming a concern to public health. Human salivary leucocytes have been proposed as a proper biological sample for the comet assay, becoming an adequate non-invasive alternative model to evaluate DNA damage. In the present study, the suitability of salivary leucocytes to respond to exposure to different nanomaterials was addressed.
