Detalhes do Documento

Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Autor(es): Taheri, Y ; Suleria, HAR ; Martins, N ; Sytar, O ; Beyatli, A ; Yeskaliyeva, B ; Seitimova, G ; Salehi, B ; Semwal, P ; Painuli, S ; Kumar, A ; Azzini, E ; Martorell, M ; Setzer, WN ; Maroyi, A ; Sharifi-Rad, J

Data: 2020

Identificador Persistente: https://hdl.handle.net/10216/143534

Origem: Repositório Aberto da Universidade do Porto

Assunto(s): Antimicrobial; Antioxidant; Cancer; Cardiovascular disease; Diabetes; Immunomodulatory; Myricetin; Neuroprotection


Descrição

Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.

Tipo de Documento Artigo científico
Idioma Inglês
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