Author(s):
Yang, Daewon ; Hashizume, Masahiro ; Tobías, Aurelio ; Honda, Yasushi ; Roye, Dominic ; Oh, Jaemin ; Dang, Tran Ngoc ; Kim, Yoonhee ; Abrutzky, Rosana ; Guo, Yuming ; Tong, Shilu ; Coelho, Micheline de Sousa Zanotti Stagliorio ; Saldiva, Paulo Hilario Nascimento ; Lavigne, Eric ; Correa, Patricia Matus ; Ortega, Nicolás Valdés ; Osorio, Samuel ; Kyselý, Jan ; Urban, Aleš ; Orru, Hans ; Indermitte, Ene ; Jaakkola, Jouni ; Ryti, Niilo ; Pascal, Mathilde ; Huber, Veronika ; Schneider, Alexandra ; Katsouyanni, Klea ; Analitis, Antonis ; Entezari, Alireza ; Mayvaneh, Fatemeh ; Goodman, Patrick ; Zeka, Ariana ; Michelozzi, Paola ; de'Donato, Francesca ; Alahmad, Barrak ; Diaz, Magali Hurtado ; la Cruz Valencia, César De ; Overcenco, Ala ; Houthuijs, Danny ; Ameling, Caroline ; Rao, Shilpa ; Nunes, Baltazar ; Madureira, Joana ; Holo-Bâc, Iulian Horia ; Scovronick, Noah ; Acquaotta, Fiorella ; Kim, Ho ; Lee, Whanhee ; Íñiguez, Carmen ; Forsberg, Bertil ; Vicedo-Cabrera, Ana Maria ; Ragettli, Martina S ; Guo, Yue-Liang Leon ; Pan, Shih Chun ; Li, Shanshan ; Sera, Francesco ; Zanobetti, Antonella ; Schwartz, Joel ; Armstrong, Ben ; Gasparrini, Antonio ; Chung, Yeonseung
Date: 2024
Persistent ID: http://hdl.handle.net/10400.18/10358
Origin: Repositório Científico do Instituto Nacional de Saúde
Subject(s): Heterogeneity; MCC; Climate Change; Human Adaptation; Minimum Mortality Temperature; Temporal Change; Determinantes da Saúde e da Doença; Avaliação do Risco
Description
Background: The minimum mortality temperature (MMT) or MMT percentile (MMTP) is an indicator of population susceptibility to nonoptimum temperatures. MMT and MMTP change over time; however, the changing directions show region-wide heterogeneity. We examined the heterogeneity of temporal changes in MMT and MMTP across multiple communities and in multiple countries. Methods: Daily time-series data for mortality and ambient mean temperature for 699 communities in 34 countries spanning 1986-2015 were analyzed using a two-stage meta-analysis. First, a quasi-Poisson regression was employed to estimate MMT and MMTP for each community during the designated subperiods. Second, we pooled the community-specific temporally varying estimates using mixed-effects meta-regressions to examine temporal changes in MMT and MMTP in the entire study population, as well as by climate zone, geographical region, and country. Results: Temporal increases in MMT and MMTP from 19.5 °C (17.9, 21.1) to 20.3 °C (18.5, 22.0) and from the 74.5 (68.3, 80.6) to 75.0 (71.0, 78.9) percentiles in the entire population were found, respectively. Temporal change was significantly heterogeneous across geographical regions (P < 0.001). Temporal increases in MMT were observed in East Asia (linear slope [LS] = 0.91, P = 0.02) and South-East Asia (LS = 0.62, P = 0.05), whereas a temporal decrease in MMT was observed in South Europe (LS = -0.46, P = 0.05). MMTP decreased temporally in North Europe (LS = -3.45, P = 0.02) and South Europe (LS = -2.86, P = 0.05). Conclusions: The temporal change in MMT or MMTP was largely heterogeneous. Population susceptibility in terms of optimum temperature may have changed under a warming climate, albeit with large region-dependent variations.
What this study adds: This study examines the geographical heterogeneity in the temporal changes in minimum mortality temperature (MMT) across 34 countries (699 communities) over the 30-year period spanning 1986–2015. This study attempts to investigate both the pooled evidence and the heterogeneity in the temporal change in MMT on a global scale. Our findings suggest an overall increase in MMT globally over the 30 years, with certain country- or region-specific trends displaying both upward and downward movements without discernible patterns. Moreover, the results indicate that the temporal change in MMT is not fully explained by the warming temperatures over time.
